Objective: The practical part is designed to achieve a working knowledge through examination of some of the basic physicochemical principles covered in the lectures of PCE242 in the delivery of drug and the design of pharmaceutical dosage forms.
Syllabus: Determination of Partial molar volumes. Boiling point elevation. Boiling point diagram of a binary mixture. Miscibility gap in a ternary system. Reaction rate and activation energy of the acid hydrolysis of ethyl acetate. Effect of ionic strength on solubility of benzoic acid in water. Adsorption isotherm. Transfer of salicylic acid across polymeric membrane(Diffusion phenomenon). Determination of Distribution Coefficient of I2 and Stability Constant of I3- Complex. Critical Micelle Concentration